FACTOR XIA IN COMPLEX WITH THE INHIBITOR methyl [(4S,8S)-8-({(2E)-3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]prop-2-enoyl}amino)-4-methyl-2-oxo-1,3,4,5,6,7,8,10-octahydro-2H-12,9-(azeno)-1,10-benzodiazacyclotetradecin-15-yl]carbamate
收藏Protein Data Bank Japan2026-02-18 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5q0e
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FACTOR XIA IN COMPLEX WITH THE INHIBITOR methyl [(4S,8S)-8-({(2E)-3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]prop-2-enoyl}amino)-4-methyl-2-oxo-1,3,4,5,6,7,8,10-octahydro-2H-12,9-(azeno)-1,10-benzodiazacyclotetradecin-15-yl]carbamate Descriptor: 1,2-ETHANEDIOL, Coagulation factor XI, SULFATE ION, ... Authors: Sheriff, S. Deposit date: 2017-05-01 Release date: 2017-07-12 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency. Bioorg. Med. Chem. Lett., 27, 2017
创建时间：
2017-05-01
