Isolation and expression profiling of circulating tumor cells in breast cancer patients part 2. Homo sapiens

We developed a method to isolate pure circulating tumor cells (CTC). RNA from such CTCs isolated from the peripheral blood of metastatic breats cnacer patients and gene expression was performed using cDNAmicroarray. we used cDNA array to compare gene expression of CTCs with normal epithelial and breast tumor samples Overall design: normal peripheral blood, normal epithelium, and CTCs