遇见数据集

Expression and alternative splicing data from 1-month-old Rbfox1 KO brain

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Rbfox1 regulates the alternative splicing of many transcripts in neurons. We have characterized the Rbfox1-dependent changes in expression and alternative splicing by comparing Rbfox1-KO brain to WT brain. In this dataset, we include the splicing and expression data obtained from dissected WT and Rbfox1 KO mouse brains. 6 total samples were analyzed: brains from 3 WT male mice and 3 Rbfox1 KO male mice, all 1 month of age.

Rbfox1可调控神经元内多种转录本的可变剪接。本研究通过对比Rbfox1敲除(Rbfox1-KO)小鼠脑组织与野生型(WT)小鼠脑组织,解析了Rbfox1依赖的基因表达与可变剪接变化。本数据集包含解剖分离的野生型与Rbfox1敲除小鼠脑组织的剪接与表达数据。本次分析共纳入6份样本,均为1月龄雄性小鼠脑组织,其中3份取自野生型小鼠,3份取自Rbfox1敲除小鼠。

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