Effect of the intrinsically disordered region (IDR) within the CLK2 (T343A) mutant in the regulation of intron retention. Effect of the intrinsically disordered region (IDR) within the CLK2 (T343A) mutant in the regulation of intron retention

We established the HeLa cells expressing the GFP (control) or CLK2 (T343A) with deletion of the IDR [T343A (dIDR)]. These cells were subjected to RNA-seq for the alternative splicing analysis. Overall design: Two HeLa cell groups (GFP, T343A (dIDR)) were subjected to RNA-seq