数据链接:
官方服务:
资源简介:
PZM21 bound Mu Opioid Receptor-Gi Protein Complex
应用场景:
创建时间:
2025-05-28
相关数据集
Discovery of Novel Multifunctional Ligands with μ/δ Opioid Agonist/Neurokinin‑1 (NK1) Antagonist Activities for the Treatment of Pain
Multifunctional ligands with agonist bioactivities at μ/δ opioid receptors (MOR/DOR) and antagonist bioactivity at the neurokinin-1 receptor (NK1R) have been designed and synthesized. These peptide-ba
Figshare2016-02-12 更新50
Molecular profiling of nociceptive brain neurons enables precision pharmacology against pain unpleasantness
Pain is a complex experience with sensory, affective, and cognitive dimensions. An ensemble of neurons in the amygdala encodes, and is causally necessary for, the unpleasant quality of pain. To determ
NIAID Data Ecosystem40
Tricyclic Triazoles as σ1 Receptor Antagonists for Treating Pain
The synthesis and pharmacological activity of a new series of 5a,7,8,8a-tetrahydro-4H,6H-pyrrolo[3,4-b][1,2,3]triazolo[1,5-d][1,4]oxazine derivatives as potent sigma-1 receptor (σ1R) ligands are
Figshare2021-04-07 更新30
Synthesis, Biological Evaluation, and Utility of Fluorescent Ligands Targeting the μ‑Opioid Receptor
Fluorescently labeled ligands are useful pharmacological research tools for studying receptor localization, trafficking, and signaling processes via fluorescence imaging. They are also employed in flu
NIAID Data Ecosystem50
Data from: G protein regulatory network shapes magnitude and kinetics of behavioral responses in an engineered opioid receptor model
G protein-coupled receptors (GPCRs) control essential neuronal functions. One GPCR with prominent effects on the nervous system and animal behavior is the mu-opioid receptor (MOR). GPCRs mediate the
DataCite Commons2026-04-22 更新40



