Lactobacillus reverses cesarean section-induced colitis susceptibility in offspring: A role in maintaining ILC3 homeostasis

The impact of microbial colonization during early life on immune system development and host health is well-established. Therefore, we investigated whether alterations in the intestinal microbiota resulting from cesarean section (CS) would affect the colonic immune system. Comparative gene expression profiling analysis of RNA-seq data for colons from adult ICR mice delivered vaginally or by CS. Both vaginal delivery (VD) and CS mice were treated with 3% DSS or normal water continuously for 8 days.