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Crystal structure of human Fgr tyrosine kinase in complex with TL02-59

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Protein Data Bank Japan2024-10-23 更新2026-04-19 收录
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Crystal structure of human Fgr tyrosine kinase in complex with TL02-59 Descriptor: 1,2-ETHANEDIOL, 3-[(6,7-dimethoxyquinazolin-4-yl)oxy]-N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-4-methylbenzamide, GLYCEROL, ... Authors: Du, S, Alvarado, J.J, Smithgall, T.E. Deposit date: 2022-05-06 Release date: 2022-12-28 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.99 Å) Cite: ATP-site inhibitors induce unique conformations of the acute myeloid leukemia-associated Src-family kinase, Fgr. Structure, 30, 2022
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2022-05-06
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