Gene expression changes in neonatal and adult plasmacytoid dendritic cells (pDC) and myeloid dendritic cells (mDC) upon TLR7/8 stimulation

Differences in gene expression changes between neonatal and adult plasmacytoid dendritic cells upon stimulation with TLR7/8 may point to specific signaling pathways which, in turn, may account for the known differential immune response of babies to vaccination or infection when compared to adults.