Late age- and dose-related effects on the proteome of thyroid tissue in rats after 131I exposure

The physiological process of iodine uptake in the thyroid is used for 131I treatment of thyroid diseases. 131I is also one of the most commonly released radionuclides after nuclear accidents. After the Chernobyl accident, the incidence rate of papillary thyroid carcinoma increased in children, possibly due to higher absorbed doses and radiosensitivity compared to adults.