LIVIA Atlas: AlphaFold-Multimer protein interaction screens resolved to residues
收藏资源简介:
Data behind LIVIA Atlas: AlphaFold-Multimer protein interaction screens scored with iLIS (AFM-LIS), keeping the interface and contact residues of every prediction. livia-atlas-human-proteome.zip: human proteome-wide screen. Schmid et al. (2025), doi:10.1101/2025.11.10.687652. livia-atlas-human-kinase-tf.zip: human kinase–transcription factor screen. Kim et al. (2025), doi:10.1101/2025.10.10.681672. livia-atlas-flypredictome.zip: FlyPredictome, Drosophila melanogaster. Kim et al. (2026), doi:10.64898/2026.04.14.718529. Keyed by FlyBase gene; identity.tsv maps every construct name to its gene, and sets.json marks subsets such as the fly kinase–TF screen (Kim et al. 2025). livia-atlas-{human,zebrafish,yeast,worm}-kinase-kinase.zip: kinase–kinase screens in human, zebrafish, yeast and C. elegans. Each zip is uncompressed, so the website reads single files by byte range. Inside: manifest.json, proteins.json, edges.tsv (pairs past the 10% FPR cutoff), and one bundle per protein in b/ (lis.py rows with residues, and a FASTA). Please cite the source of each screen. Version 1.1: FlyPredictome constructs carry the sequences that were folded and are placed on their genes by sequence; kinase–kinase screens added. Version 1.2: a gene whose isoforms were folded separately keeps one bundle per isoform, so a page can read the reference first: b/<gene>.zip holds the reference and an isoforms.json listing the others, each in b/<gene>~<k>.zip.



