Survival of fipA, and ΔfipAB mice after intranasal inoculation.

1C57/BL6 mice were intranasally challenged with the indicated inoculum dose, which was confirmed by plating the inoculum.2Indicates the number of days after challenge that mice showed the first signs of irreversible mortality, and were euthanized. Mice were followed for a minimum of 20 days. Similar to the ΔfipAB mutant, mice similarly challenged with the ΔfipB mutant survive for more than 30 days without any signs of infection [14].