Synovial fluid and blood neutrophils from rheumatoid arthritis patients and matched healthy controls

Synovial fluid and blood neutrophils from 7 rheumatoid arthritis patients and 5 matched healthy controls Experiment designed to compare gene signatures of neutrophils isolated from site of pathiology (synovial fluid (SF)) and from peripheral blood (PB) of RA patients. Neutrophils were isolated from SF and PB from the same individuals (n = 3) to provide paired sample analysis. Neutrophils were also isolated from PB from healthy donors as controls. There are two technical replicates for each donor and tissue. The technical replicates were made by running the same library in two lanes.