Study of the viral and microbial metagenomes associated with the Crohn's disease. Crohn's Disease viral and microbial metagenome

Healthy adult controls and patients affected by ileocolic Crohn’s disease from Valencia (Spain) were examined for their viral and microbial communities from feces and, in one additional case, present in the intestinal tissue. The taxonomical and functional analyses on unassembled and assembled sequence reads, following two different approaches allows as to compare the viral and microbial communities between both groups in study in several ways. For example we compared by group (controls vs patients), by entity (viruses vs bacteria), by reads assembly (assembled vs unassembled reads) and by methodology (our approach vs an existing pipeline).