Epigenetic clock estimations in patients with isolated REM Sleep Behavior Disorder
收藏Zenodo2022-05-16 更新2026-05-25 收录
下载链接：
https://zenodo.org/record/6546164
下载链接
链接失效反馈官方服务：
资源简介：
Isolated REM Sleep Behavior Disorder (iRBD) is the strongest prodromal marker for conversion to α-synucleinopathies. A continuum between aging and neurodegeneration has been proposed, but this hypothesis has not been tested in iRBD so far. Here we used epigenetic clocks, estimated from DNA methylation arrays using the DNA Methylation Age Calculator available at https://dnamage.genetics.ucla.edu/home, to measure biological aging in videopolysomnography-confirmed iRBD patients (iRBDs, n=28), videopolysomnography-negative controls (CTR_neg; n=57), and controls from the general population (CTR_pop; n=31)<strong>.</strong>
提供机构：
Zenodo
创建时间：
2022-05-16
