Correspondence between the radius at which is maximized and the radius of aggregates at binary and non-binary fields of view.

Each result displayed represents the average of 30 simulated fields of view using the exact same experimental parameters. Panel A: Simulations were applied at very low event densities (0.01 particles per pixel) with and without a diffuse pool. Left—Sample simulated fields of view. The image intensities have been rescaled for display purposes. Right—Corresponding profile. Panel B: Simulations were applied at high event densities (10 particles per pixel) with and without a diffuse pool. For simulations where a diffuse pool is present, the Aggregate-to-Diffuse ratio (ADR) and Signal-to-Background ratio (SBR) were set at 0.05 and 3, respectively. Left—Sample simulated fields of view. Right—Corresponding profile.