Crystal structure of TEAD3 in complex with IAG933
收藏Protein Data Bank Japan2024-08-07 更新2026-04-19 收录
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Crystal structure of TEAD3 in complex with IAG933 Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 4-[(2~{S})-5-chloranyl-6-fluoranyl-2-phenyl-2-[(2~{S})-pyrrolidin-2-yl]-3~{H}-1-benzofuran-4-yl]-5-fluoranyl-6-(2-hydroxyethyloxy)-~{N}-methyl-pyridine-3-carboxamide, DIMETHYL SULFOXIDE, ... Authors: Scheufler, C, Villard, F, Chau, S. Deposit date: 2023-05-10 Release date: 2024-04-10 Last modified: 2024-08-07 Method: X-RAY DIFFRACTION (1.961 Å) Cite: Direct and selective pharmacological disruption of the YAP-TEAD interface by IAG933 inhibits Hippo-dependent and RAS-MAPK-altered cancers. Nat Cancer, 5, 2024
创建时间：
2023-05-10
