Single-cell RNA-seq of hESC-derived, differentiating cardiac cells on day 2, 3 and 8; control and PD0325901-treated.
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https://www.ncbi.nlm.nih.gov/sra/ERP144969
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资源简介：
The role of FGF-MEK-ERK signalling pathway during embryonic heart development has not been fully elucidated. Here, we inhibited the pathway for 1 day using PD0325901, a MEK inhibitor, at the lateral plate mesoderm stage during cardiac differentiation of human embryonic stem cells. Cells were collected on day 2 (before PD0325901 administration), day 3 and day 8 to determine the effect of a transient FGF-MEK-ERK pathway modulation on the cardiac cell fate choice.
创建时间：
2023-10-13
