RBD loop2 plasticity is a key determinant for HKU5 coronavirus emergence in mink

This repository contains AlphaFold3 (AF3 v4) structural prediction outputs generated for HKU5-related coronavirus receptor-binding domain interactions with ACE2 orthologs. Included are raw prediction outputs for wild-type and mutant RBD–ACE2 complexes, confidence metrics (pTM and ipTM), predicted co-structures, and replicate predictions generated across multiple random seeds. Predictions include interactions with human (Homo sapiens), mink (Neogale vison), and bat (Pipistrellus abramus) ACE2 orthologs. Analysis scripts, workflows, and datasets are available in the associated GitHub repository: https://github.com/TheSatoLab/nvHKU5_emergence