Effect of various MGO concentrations on contents of total cholesterol, LDL- cholesterol and triglycerides in the plasma of Triton WR-1339 treated rats.

The placebo (control) group (A) was administered 1 ml carrier alone. The Triton WR-1339 group (B) was administered 1 ml carrier and one hour later 1 ml of Triton WR-1339 (200 mg/kg). The MGO-treated group (C) received a dose of MGO and one h later a single dose of Triton WR-1339. MGO was administered at 2.5%, 4%, 5% and 7.5% (v/v) in 1 ml carrier. Controls and MGO were injected intraperitoneally. Twenty-four h later, blood was collected from the hearts of animals in heparinized tubes and plasma samples were prepared and assayed for total cholesterol, LDL-cholesterol, and triglycerides. The values represent mean ± SD of six rats. Significantly different values were obtained from MGO-treated rats as compared to Triton WR-1339 treated rats with pp>0.05).