Effects of the FOXF1 on herpes simplex virus 1 and host chromatin accessibility in Neuro-2a cells

This is a part of the study that shows that a host gene,FOXF1, promote herpes simplex virus 1 (HSV-1) genome accessibility. These ATAC analyses viral and host genome accessibility in Neuro-2a cells. Neuro-2a cells were transfected with pFOXF1 and pcDNA plasmids for 42 hours then infected with herpes simple virus1 for 3 hours. Overall design: P represents cell samples transfected with pcDNA plasmid as control group. F represents cell samples transfected with pFOXF1 plasmid as the experimental group.Comparison of cells overexpressing FOXF1 with control cells. Infect the cells for viral and host genome accessibility identification