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Crystal structure of Bcl-xL in complex with compound 10

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Protein Data Bank Japan2023-11-08 更新2026-03-21 收录
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Crystal structure of Bcl-xL in complex with compound 10 Descriptor: 7-(4-{[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrophenyl)sulfonyl]carbamoyl}-2-methylphenyl)-3-[3-(naphthalen-1-yloxy)propyl]pyrazolo[1,5-a]pyridine-2-carboxylic acid, Bcl-2-like protein 1, PHOSPHATE ION Authors: Sogabe, S, Igaki, S, Hayano, Y. Deposit date: 2013-09-26 Release date: 2013-11-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Discovery of potent Mcl-1/Bcl-xL dual inhibitors by using a hybridization strategy based on structural analysis of target proteins. J.Med.Chem., 56, 2013
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2013-09-26
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