Hyperactive Rac stimulates cannibalism of living target cells and enhances CAR-M-mediated cancer cell killing

NIAID Data Ecosystem2026-05-01 收录

细胞免疫治疗

CAR-M免疫疗法

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE247106 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2024-01-03

Suboptimal Activation of Antigen-Specific CD4+ Effector Cells Enables Persistence of M. tuberculosis In Vivo

牛结核病与副结核病免疫机制

细胞免疫治疗

Adaptive immunity to Mycobacterium tuberculosis controls progressive bacterial growth and disease but does not eradicate infection. Among CD4+ T cells in the lungs of M. tuberculosis-infected mice, we

Figshare2016-01-18 更新60

Programme of Self-Reactivity for Innate-Like T Cell-Mediated Cancer Immunosurveillance

肿瘤免疫学

细胞免疫治疗

The concept of cancer immunosurveillance ascribes a role of cellular immunity in eliminating transformed cells with cytotoxic CD8+ T cells being a primary mediator. Cancer cells can express neoantigen

NIAID Data Ecosystem40

Anti-Leukemia Activity of In Vitro-Expanded Human Gamma Delta T Cells in a Xenogeneic Ph+ Leukemia Model

细胞免疫治疗

白血病治疗

Gamma delta T cells (GDTc) lyse a variety of hematological and solid tumour cells in vitro and in vivo, and are thus promising candidates for cellular immunotherapy. We have developed a protocol to ex

Figshare2016-01-18 更新30

Clinical optimization and molecular characterization of an engineered Type-1 regulatory T cell therapy. Clinical optimization and molecular characterization of an engineered Type-1 regulatory T cell therapy

细胞免疫治疗

转录组学分析

purpose: To investigate transcriptional changes in engineered Tr1 Cells Methods: RNA sequencing of polyA enriched donor matched CD4 T cells lentiviral transduced with human IL-10 (CD4IL-10) or control

NIAID Data Ecosystem50

Table_1_Combined Effects of HLA-B*57/5801 Elite Suppressor CD8+ T Cells and NK Cells on HIV-1 Replication.DOCX

HIV免疫控制机制

细胞免疫治疗

Elite controllers or suppressors (ES) are HIV-1 infected individuals who maintain undetectable viral loads without anti-retroviral therapy. The HLA-B*57 allele is overrepresented in ES suggesting a ro

NIAID Data Ecosystem40

Hyperactive Rac stimulates cannibalism of living target cells and enhances CAR-M-mediated cancer cell killing

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