Crhr1

ENCODES a protein that exhibits corticotropin-releasing hormone binding; corticotropin-releasing hormone receptor activity; G protein-coupled receptor activity; INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; behavioral response to cocaine; PARTICIPATES IN corticotropin-releasing hormone signaling pathway; G protein mediated signaling pathway via Galphas family; long term depression; ASSOCIATED WITH increased alcohol consumption; increased thigmotaxis; ASSOCIATED WITH Binge Drinking; Cocaine-Related Disorders; depressive disorder; FOUND IN apical part of cell; dendrite; multivesicular body; INTERACTS WITH (R)-noradrenaline; 2,4,6-trinitrobenzenesulfonic acid; ammonium chloride

编码一种表现出皮质醇释放激素结合特性的蛋白质；皮质醇释放激素受体活性；G蛋白偶联受体活性；参与腺苷酸环化酶激活的G蛋白偶联受体信号通路；腺苷酸环化酶调节的G蛋白偶联受体信号通路；对可卡因的行为反应；参与皮质醇释放激素信号通路；通过Galpha家族介导的G蛋白信号通路；长期压抑；与酒精摄入增加、增强趋触性相关；与暴饮、可卡因相关障碍、抑郁障碍相关；存在于细胞顶端部分、树突、多泡体中；与（R）-去甲肾上腺素、2,4,6-三硝基苯磺酸、氯化铵相互作用。