This is a raw data and supplemental information of the manuscript "Specific macrophage RhoA targeting (SMART) CRISPR-Cas9 for mitigating osteoclastogenesis-induced joint damage in inflammatory arthrit
Polymers with a very balanced hydrophilicity can translocate through biological membranes without doing damage. This simulates natural metabolism, and, therefore, allow for targeting certain drugs or
Copyright information: Taken from "Increased lymphangiogenesis in joints of mice with inflammatory arthritis"http://arthritis-research.com/content/9/6/R118Arthritis Research & Therapy 2007;9
Macrophages are main drivers of inflammation and tissue damage in autoimmune diseases including rheumatoid arthritis. The rate-limiting step for transcription of >70% of inducible genes in macrophages
