Predicting patients who would benefit from oesophagectomy following neoadjuvant chemoradiotherapy based on baseline total lesion glycolysis

The study investigates the relationship between baseline pre-treatment total lesion glycolysis (TLG) and overall outcomes in patients who underwent neoadjuvant therapy followed by oesophagectomy. It discusses the utility of percentage change in TLG as response to neoadjuvant therapy and its clinical relevance. It also highlights how volumetric metabolic parameters play a role in developing individualised treatment pathways to predict which patient would benefit from oesophagectomy following neoadjuvant treatment.