Crystal structure of TTK kinase domain in complex with compound 30
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Crystal structure of TTK kinase domain in complex with compound 30 Descriptor: 2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-4-(oxan-4-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Dual specificity protein kinase TTK, MAGNESIUM ION Authors: Kim, H.L, Cho, H.Y, Park, Y.W, Lee, Y.H, Ko, E.H, Choi, H.G, Son, J.B, Kim, N.D. Deposit date: 2020-07-06 Release date: 2021-05-12 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: X-ray Crystal Structure-Guided Design and Optimization of 7 H -Pyrrolo[2,3- d ]pyrimidine-5-carbonitrile Scaffold as a Potent and Orally Active Monopolar Spindle 1 Inhibitor. J.Med.Chem., 64, 2021
创建时间：
2020-07-06
