Anti-inflammatory Labdane Diterpenoids from Lagopsis supina
收藏Figshare2016-02-17 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Anti_inflammatory_Labdane_Diterpenoids_from_i_Lagopsis_supina_i_/2302912
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Ten new labdane diterpenoids, lagopsins A–H (1–3, 5, 7–10) and 15-epi-lagopsins C and D (4, 6), together with five known labdane diterpenoids (11–15), were isolated from the whole plants of Lagopsis supina. The absolute configuration of lagopsin A (1) was determined by single-crystal X-ray crystallographic analysis. Compounds 7, 9, 13, and 15 exhibited moderate inhibition of nitric oxide production stimulated by lipopolysaccharide in BV-2 microglial cells with IC50 values in the range 14.9–34.9 μM.
创建时间：
2016-02-17
