Molecular heterogeneity and commonalities in pancreatic cancer precursors with gastric and intestinal phenotype

A comparative morpho-genetic analysis of PDAC precursors aiming at dissecting the process of carcinogenesis and tackling the heterogeneity of preinvasive lesions was performed Overall design: RNA-sequencing of human PDAC precursor lesions (gastric and intestinal IPMN; PanIN), bulk acinus and PDAC