Age at menarche and its association with selected cardiovascular risk factors and components of the metabolic syndrome.

Abbreviations: CI: Confidence Interval, BMI: Body mass index, HDL: High density lipoprotein, lsmean: least square means.*the p-values for trend are reported for age at menarche as continuous variable.**2-h glucose: glucose 2 hours after an oral glucose challenge; n = 1417 due to the non-performance of the oGTT in people with diagnosed diabetes.Model 1: results were adjusted for age (in years).Model 2: “complete model” results were adjusted for age (in years), number of pregnancies (no pregnancy, 1–2 pregnancies, more than 2 pregnancies), ever use of oral contraceptives, ever use of hormone replacement therapy, physical activity (less and more than one hour per week), smoking habits (current or no current smoking) and alcohol intake (more than 20 g per day).Model 3: “complete plus BMI change” results were adjusted for all variables in model 2 plus the BMI change since age 25 years.