Rescue of fragile X syndrome by CRISPR activation of the ribosome associated quality control factor ASCC3
收藏Mendeley Data2026-04-18 收录
官方服务:
资源简介:
Original blots and Mass spectrometry data
应用场景:
创建时间:
2025-04-30
相关数据集
AAV-delivered diacylglycerol kinase DGKk achieves long-term rescue of fragile X syndrome mouse model
Fragile X syndrome (FXS) is the most frequent form of familial intellectual disability. FXS results from the lack of the RNA binding protein FMRP and is associated with the deregulation of signaling p
NIAID Data Ecosystem80
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells
The aim of this work is to selectively increase transcription from the FMR1 locus in FXS hESC lines using CRISPR-Cas9 fused to transcriptional activators. Endonuclease deficient Cas9 (dCas9) was fused
NIAID Data Ecosystem50
Table_1_Targeted Reactivation of FMR1 Transcription in Fragile X Syndrome Embryonic Stem Cells.XLSX
Fragile X Syndrome (FXS) is the most common inherited cause of intellectual disability and autism. It results from expansion of a CGG nucleotide repeat in the 5′ untranslated region (UTR) of FMR1. Lar
NIAID Data Ecosystem30
Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene [methylation]. Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene [methylation]
Fragile X syndrome (FXS), the most common genetic form of intellectual disability in male, is caused by silencing of the FMR1 gene by hypermethylation of the CGG expansion mutation in the 5’UTR region
NIAID Data Ecosystem60
Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene [methylation]
Fragile X syndrome (FXS), the most common genetic form of intellectual disability in male, is caused by silencing of the FMR1 gene by hypermethylation of the CGG expansion mutation in the 5’UTR region
NIAID Data Ecosystem40



