Management of Pediatric Atopic Dermatitis with Systemic Biologics: An Evidence-Based Review

Atopic dermatitis (AD) is a common chronic inflammatory skin disease characterized by typical eczematous morphology and intense pruritus with onset before 5 years of age in up to 90% of cases. The physical and psychosocial burden can have a significant negative impact on quality of life. This systematic review examines the available evidence for systemic biologics in pediatric patients with AD.

特应性皮炎（AD）是一种常见的慢性炎症性皮肤病，其特征为典型的湿疹形态和剧烈的瘙痒，90%的病例在5岁之前发病。该疾病的身体和心理社会负担可能对生活质量产生显著的负面影响。本次系统综述旨在考察针对特应性皮炎儿童患者的系统性生物疗法的现有证据。