One-Pot Asymmetric Synthesis of Substituted Piperidines by Exocyclic Chirality Induction
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https://figshare.com/articles/dataset/One_Pot_Asymmetric_Synthesis_of_Substituted_Piperidines_by_Exocyclic_Chirality_Induction/2852698
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资源简介：
A highly efficient one-pot synthesis of substituted piperidines was developed through nitroalkene, amine, and enone condensation. The transformation was suitable for a large group of substrates, giving excellent yields and diastereoselectivity. Reactions using chiral amines revealed a chirality induction through the unusual exocyclic stereochemistry control, producing enantiomeric pure piperidines in simple steps.
创建时间：
2016-02-26
