Data from: Analysis and visualization of H7 influenza using genomic, evolutionary and geographic information in a modular web service

We have reported previously on use of a web-based application, Supramap
(http://supramap.org) for the study of biogeographic, genotypic, and
phenotypic evolution. Using Supramap we have developed maps of the spread
of drug-resistant influenza and host shifts in H1N1 and H5N1 influenza and
coronaviruses such as SARS. Here we report on another zoonotic pathogen,
H7 influenza, and provide an update on the implementation of Supramap as a
web service. We find that the emergence of pathogenic strains of H7 is
labile with many transitions from high to low pathogenicity, and from low
to high pathogenicity. We use Supramap to put these events in a temporal
and geospatial context. We identify several lineages of H7 influenza with
biomarkers of high pathogenicity in regions that have not been reported in
the scientific literature. The original implementation of Supramap was
built with tightly coupled client and server software. Now we have
decoupled the components to provide a modular web service for POY
(http://poyws.org) that can be consumed by a data provider to create a
novel application. To demonstrate the web service, we have produced an
application, Geogenes (http://geogenes.org). Unlike in Supramap, in which
the user is required to create and upload data files, in Geogenes the user
works from a graphical interface to query an underlying dataset. Geogenes
demonstrates how the web service can provide underlying processing for any
sequence and metadata database.