Summary of adhesome components detected in RPM-1 AP-proteomics using C. elegans.
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Shown are cumulative results from seven independent RPM-1 AP-proteomics experiments. Reported are total peptide spectra for adhesome components enriched 1.5x in either GS::RPM-1 or GS::RPM-1 LD over GS::GFP negative control samples. Note adhesome components do not show more than 2 fold increase in GS::RPM-1 LD substrate ‘trap’ compared to GS::RPM-1 samples suggesting they are not likely to be ubiquitination substrates. Significance determined using Mann-Whitney test (p-value) and corrected for multiple comparisons using post hoc Benjamini-Hochberg method (q-value) with a 5% false discovery rate (FDR). For statistical comparison and fold enrichment, normalized values are used (see Methods and S1 and S2 Data). ***p
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2024-12-13
