Comparison of network metrics with longitudinal scans between male (n = 12) and female (n = 14).

The statistical results were computed with a two-way linear mixed model with longitudinal time as within-subject fact, gender as between-subject factor and time by gender as interaction. The effect of age at 1st scan, handedness, education level, and brain size were adjusted for all of these analyses. Post-hoc results of the global topological measures were detailed in Fig. 4. Bold indicates variables that are statistically significant (p italic indicates variables that show trend of significance (p Comparison of network metrics with longitudinal scans between male (n = 12) and female (n = 14).