Effect of Ethanol Leaf Extract of Senegal Lilac Lonchocarpus Sericeus (Poir) On Indomethacin Induced Gastric Ulcer in Wister Rats.

Senegal lillac (lonchocarpus sericeus (Poir.)) a medicinal plant with long history in folkloric medicine, has been used in the treatment of pathological conditions such as ulceration of the gastric gland (gastric ulcer). Due to this remarkable medicinal properties of this plant, this study was designed to scrutinize the Therapeutic Potentials of the Ethanol Leaf Extract of Senegal lillac (lonchocarpus sericeus) [ELL] on indomethacin-induced Gastric ulcer in rat’s model it also create the opportunity to clinically investigate the presence of bioactive compound in the leaf extract of Senegal lillac (lonchocarpus sericeus) which are formed as a secondary metabolite by the plant. The experimental design consist of 40 Albino rats divided into 5 groups of 8 rats each. Indomethacin was administered intraperitoneally as a single dose followed by oral administration of ELL with doses of 62.5 and 125mg/kg BWT and 20mg/kg BWT of ranitidine for 28days.