Triggers of Thyroid Cancer Diagnosis

this is a supplement
of A Systematic Review and Meta-analysis.

The incidence of thyroid
cancer has increased worldwide. In the United States, for instance,
the incidence of thyroid cancer increased from a 4.9 to 14.2 per 100,000
person-years over the last two decades, while in South Korea, on the other
hand, thyroid cancer increased by more than seven fold, from 6.3 per 100,000
person year in 1999 to 47.5 per 100,000 population in 2009.

Understanding the method
of thyroid cancer detection has potential implications on interpreting
incidence rates, the diagnosis and management of thyroid cancer. The aim of
this study is to summarize the available evidence to assess the frequency of
incidental (asymptomatic) and non-incidental TC and examine the triggers that
lead to diagnosis with comparison across multiple cohorts.