Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with Se-cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with Se-cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution Descriptor: (4S,5aS,8S,8aR)-4-(2-methylpropyl)-N-[(1R,5Z,7R,8R,9R,10R,11S,12R)-10,11,12-trihydroxy-7-methyl-13-oxa-2-selenabicyclo[7.3.1]tridec-5-en-8-yl]octahydro-2H-oxepino[2,3-c]pyrrole-8-carboxamide (non-preferred name), 16S Ribosomal RNA, 23S Ribosomal RNA, ... Authors: Aleksandrova, E.V, Wu, K.J.Y, Robinson, P.J, Benedetto, A.E, Yu, M, Tresco, B.I.C, See, D.N.Y, Jiang, T, Ramkissoon, A, Dunand, C.F, Svetlov, M.S, Lee, J, Myers, A.G, Polikanov, Y.S. Deposit date: 2024-08-07 Release date: 2025-08-27 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Why Sulfur is Important in Lincosamide Antibiotics. Chem, 11, 2025