To Study Prevalence and Pattern of Psychiatric Comorbidities among Thyroid Dysfunction Patients at Tertiary Care Hospital

Abstract:Thyroid hormones can directly or indirectly affect almost all systems in the body, therefore changes in theirserum levels can have negative effect on human health. Various types of thyroid disorders have been observedin 5%–10% of the population. There is limited literature on the rates of thyroid dysfunction among patients withmajor psychiatric disorders in the Indian population. This study aims to study prevalence and pattern ofpsychiatric comorbidities among thyroid dysfunction patients at tertiary care hospital.Methodology: The study was a observational study, which was conducted at R.D. Gardi Medical College,Ujjain. A sample size of 161 was calculated. Thyroid dysfunction patients attending the OPD and also thoseadmitted in IPD of C. R. Gardi hospital were studied. Clinical information were obtained by interviewing. BriefPsychiatric Rating Scale (BPRS), Hamilton Anxiety Rating Scale (HAM-A), Hamilton Depression Rating Scale(HAM-D), Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5) based diagnostic criteriafor clinical evaluation of psychiatric conditions was used.Result: Among 161 study participants, 113 (70.2%) were females and 48 (29.8%) were males. Mean age ofpresentation was 40.81 years (SD 13.322). Hypothyroidism was present in 142 patients (88.2%) andhyperthyroidism was present in 19 patients (11.8%). In our study population it was found that 83 (51.6%)cases had psychiatric comorbidity. In the hypothyroid group, psychiatric comorbidity was present in 72 (50.7%)patients. In hyperthyroid group, psychiatric comorbidity was present in 11 (57.9%) patientsConclusion: Thyroid dysfunction is commonly associated with comorbid psychiatric disorder. So timelydetection and treatment of psychiatric comorbidities are very necessary while treating the patients of thyroiddysfunction. Our study identify high Psychiatric comorbidities in the thyroid dysfunction patients.