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Structure determination of Aurora Kinase in complex with inhibitor

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Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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Structure determination of Aurora Kinase in complex with inhibitor Descriptor: 2-(1H-pyrazol-3-yl)-1H-benzimidazole, SERINE/THREONINE-PROTEIN KINASE 6 Authors: Howard, S, Berdini, V, Boulstridge, J.A, Carr, M.G, Cross, D.M, Curry, J, Devine, L.A, Early, T.R, Fazal, L, Gill, A.L, Heathcote, M, Maman, S, Matthews, J.E, McMenamin, R.L, Navarro, E.F, O'Brien, M.A, O'Reilly, M, Rees, D.C, Reule, M, Tisi, D, Williams, G, Vinkovic, M, Wyatt, P.G. Deposit date: 2008-10-17 Release date: 2009-01-27 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.97 Å) Cite: Fragment-Based Discovery of the Pyrazol-4-Yl Urea (at9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity. J.Med.Chem., 52, 2009
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2008-10-17
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