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Aurora A Kinase Inhibition Induces Accumulation of Tumor Cells in Mitosis with Restored Interferon Signaling to Potentiate Response to PD-L1 Immune Checkpoint Blockade [RNA-seq]

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP400652
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资源简介:
By arresting tumor cells in mitosis, aurora A kinase inhibition restores interferon signaling in small cell lung cancer tumor cells and cooperates with PD-L1 immune checkpoint blockade. Overall design: Bulk RNA sequencing in primary mouse small cell lung cancer cells (SCLC) derived from SCLC genetically-engineered mouse models that are treated with Aurora A Kinase inhibitor.
创建时间:
2023-12-15
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