KPC-2 F72Y mutant with acylated imipenem
收藏Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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https://pdbj.org/mine/summary/7llh
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KPC-2 F72Y mutant with acylated imipenem Descriptor: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, Carbapenem-hydrolyzing beta-lactamase KPC Authors: Furey, I, Palzkill, T, Sankaran, B, Hu, L, Prasad, B.V.V. Deposit date: 2021-02-03 Release date: 2021-05-26 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Local interactions with the Glu166 base and the conformation of an active site loop play key roles in carbapenem hydrolysis by the KPC-2 beta-lactamase. J.Biol.Chem., 296, 2021
创建时间：
2021-02-03
