Model design choices impact biological insight: Unpacking the broad landscape of spatial-temporal model development decisions: CELL VARIABILITY

Data and results for CELL VARIABILITY simulations.

Simulations of cancerous cells in colony and tissue contexts with and without age and volume variability. Each condition is run for 15 days (21600 ticks) with 50 replicates (random seeds 0 - 49). Cancerous cells (max_height x 1.5, meta_pref x 1.5, migra_threshold x 0.5) are introduced to the center of the environment after a 1 day delay. Snapshots are taken every 0.125 days (180 ticks).

The data folder contains .tar.xz compressed replicate sets. The results folder contains .csv.xz files of compressed parsed data.

Simulations are labelled as: [context]_[age]_[volume]

- [context]
- C = colony context, cancerous cells only
- CH = tissue context, cancerous cells and healthy cells
- [age]
- A0 = deterministic age (all initial ages set to zero)
- A1 = stochastic age (ages drawn from uniform distribution)
- [volume]
- V0 = deterministic volume (all initial volumes set to average volume)
- V1 = stochastic volume (volumes drawn from normal distribution)

本数据集包含了在殖民地和组织环境中，考虑或忽略年龄和体积变异性下癌细胞模拟的数据和结果。
每个条件均运行15天（21600个时间步长），并进行了50次重复实验（随机种子0-49）。在第1天延迟后，将具有特定参数（最大高度 x 1.5，元偏好 x 1.5，迁移阈值 x 0.5）的癌细胞引入环境中心。每0.125天（180个时间步长）进行一次快照。
数据文件夹包含经过.tar.xz压缩的重复实验集。结果文件夹包含压缩的解析数据.csv.xz文件。
模拟标签形式为：[环境]_[年龄]_[体积]

- [环境]
- C = 殖民地环境，仅包含癌细胞
- CH = 组织环境，包含癌细胞和健康细胞

- [年龄]
- A0 = 确定性年龄（所有初始年龄设置为零）
- A1 = 随机年龄（年龄从均匀分布中抽取）

- [体积]
- V0 = 确定性体积（所有初始体积设置为平均体积）
- V1 = 随机体积（体积从正态分布中抽取）