Structure of T790M EGFR kinase domain co-crystallized with dacomitinib
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Structure of T790M EGFR kinase domain co-crystallized with dacomitinib Descriptor: (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide, Epidermal growth factor receptor Authors: Gajiwala, K.S, Feng, J, Ferre, R, Ryan, K, Brodsky, O, Stewart, A. Deposit date: 2012-11-21 Release date: 2013-01-16 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Insights into the Aberrant Activity of Mutant EGFR Kinase Domain and Drug Recognition. Structure, 21, 2013
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2012-11-21
