Spatiotemporal dysregulation of neuron-glia related genes and pro-/anti-inflammatory miRNAs in the 5xFAD mouse model of Alzheimer's disease - Supplementary data

Supplementary Table 1.  Gene expression profile  by RT-qPCR analysis revealed no significant differences when simultaneously considering the genotype (WT/5xFAD), age (6/9 months) and brain region (HPC, hippocampus/PFC, prefrontal cortex). 

Supplementary Table 2.  miRNA-target table for the Analyzed microRNAs and targets selected for this study. Obtained in the online platform https://www.mirnet.ca/

Supplementary Table 3.  Node table for the analyzed microRNAs and targets selected for this study. We only considered miRNAs and/or targets with a node degree of at least 2. Obtained in the online platform https://www.mirnet.ca/

Supplementary Table 4.  Bivariate Pearson’s correlation coefficients and respective p-values obtained between all miRNAs and genes.

Supplementary Table 5.   List of microRNAs analyzed by RT-qPCR and their primer sequences.

Supplementary Table 6.  List of genes and respective primer sequences used for mRNA analysis by RT-qPCR.

Supplementary Table 7.  Raw data used for correlational analysis in hippocampus (HPC) and prefrontal cortex (PFC) using the cor function in RStudio software.