Genome-scale CRISPR knockout screen for a Dengue virus mutant
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Genome-scale CRISPR knockout screen for a Dengue virus mutant
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2023-06-30
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Additional file 1 of CoRe: a robustly benchmarked R package for identifying core-fitness genes in genome-wide pooled CRISPR-Cas9 screens
Additional File 1: Table S1. All compared sets of core-fitness and common-essential genes with annotations.
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List of guideRNAs used for validation.
While SARS-CoV-2 primarily infects the respiratory tract, clinical evidence indicates that cells from diverse cell types and organs are also susceptible to infection. Using the CRISPR activation (CRIS
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Effect of CRISPR activation of Zbtb7b, Vps72, Gba, or Mrpl9 in liver tumorigenesis in mice
Hepatocellular carcinomas (HCCs) undergo chromosomal amplifications with resultant increases in gene expression levels, yet the impact of these changes remains largely unknown. We sought to identify c
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Identification of Functional Genetic Components modulating Cellular Toxicity Response to PFOS using Genome-wide CRISPR Screens
Per- and polyfluoroalkyl substances (PFAS) are a group of chemicals that pose significant health and environmental risks due to their persistence and widespread use. These substances, known for their
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Differential gene expression (FDR 0.05) for CRISPR edited clones.
hTLR4 Cells were transfected a CRISPR/Cas9 construct and a gRNA specific for the rs17622517 locus. Wild type, heterozygous or homozygous clones were isolated and then treated with no LPS, LPS for 90 m
Figshare2021-07-27 更新10
