Mechanomics RT-DC Set 02 - Carcinoma

Entry is a part of Mechanomics collection (10.6084/m9.figshare.c.5399826) that contains materials supporting findings presented in the following manuscript: Urbanska, M., Ge, Y. et al., De novo identification of universal cell mechanics gene signatures BiorXiv: https://doi.org/10.1101/2021.04.26.441418; first published: 27th April 2021, last updated: 4th Nov 2024 eLife: https://doi.org/10.7554/eLife.87930; first published: 23rd March 2023, last updated: 27th Dec 2024 This dataset contains mechanical measurement of six carcinoma cell lines obtained from RIKEN institute: • ECC4 (RCB0982) - intestine - small-cell carcinoma • TGBC18TKB (RCB0982) - intestine - adenocarcinoma • WA-hT (RCB2279) - lung - small-cell carcinoma • EBC-1 (RCB1965) - lung - squamous cell carcinoma* • A549 (RCB0098) - lung - adenocarcinoma • ECC10 (RCB0983) - stomach - small-cell carcinoma • MKN45 (RCB1001) - stomach - adenocarcinoma • MKN1 (RCB1003) - stomach - adenocarcinoma. *this dataset was removed from later versions of the manuscript Measurements were performed using real-time deformability cytometry (RT-DC). _rtdc.zip - contains data acquired during the measurments in '*.rtdc' format _tsv.zip - contains extended data in a '*.tsv' format _glmm.zip - contains result summaries of statistical analysis comparing Young's moduli of the different cell types using generalised linear mixed effects models