Crystal structure of PDE10 in complex with inhibitor AF-399/14387019
收藏Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Crystal structure of PDE10 in complex with inhibitor AF-399/14387019 Descriptor: 2-[2-(4-phenyl-5-sulfanylidene-4,5-dihydro-1H-1,2,4-triazol-3-yl)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione, MAGNESIUM ION, ZINC ION, ... Authors: Huang, Y.Y, Yu, Y.F, Zhang, C, Wu, D, Wu, Y, Luo, H.B. Deposit date: 2018-10-10 Release date: 2019-04-10 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors. J. Med. Chem., 62, 2019
创建时间:
2018-10-10



