Molecular Signatures of Tumour and its Microenvironment for Precise Quantitative Diagnosis of Oral Squamous Cell Carcinoma: An Interna-tional Multi-cohort Diagnostic Validation Study

<strong>Supplementary Materials: </strong>The following supporting information can be downloaded at: www.mdpi.com/xxx/s1, <strong>Table ST1</strong> – qMIDS^V2Gene panel primer sequences; <strong>Figure S1</strong> – qMIDS^V1 vs qMIDS^V2 384-well assay format and protocols; <strong>Figure S2.</strong> Individual target gene expression pattern in 1761 samples; <strong>Figure S3.</strong> Various statistical methods used for gene selection analysis on 1761 clinical samples; <strong>Figure S4. </strong>Diagnostic performance comparison between qMIDS^V2 vs qMIDS^V2*(with 4 less effective genes removed from the panel of 14 target genes of qMIDS^V2); <strong>Figure S5</strong>. Effect of removing individual genes from the 14-target gene panel qMIDS^V2 (qV2) on diagnostic test performance based on the UK patient cohort data.