Comparison of the Clinical Efficacy and Pregnancy Outcomes between LEEP and Stratified Incision in the Management of Cervical Intraepithelial Lesions

The purpose of this study was to evaluate the effects of conical resection and stratified resection of cervical lesions on the diagnosis and treatment of cervical lesions as well as on cervical morphology and pregnancy outcome. A total of 258 patients who underwent circular electroresection (LEEP) for high-grade cervical intraepithelial lesions from 2018 to 2023 were divided into two groups: conventional cone resection group (n = 105) and modified stratified resection group (n = 153). The diameter of the lesion area, the depth of cervical canal resection, the volume of excised tissue, the postoperative pathological margin, cervical shortening, cytology, colposcopy reexamination, postoperative fertility and delivery mode were recorded until March 2025. By comparing the tissue volume of diseased cervical conization group (P<0.01), the postoperative 1cm of cervical vaginal segment was shorter than that of preoperative cervicovaginal segment, and the stratified resection group was better (P<0.001). In patients with fertility requirements after operation, the premature delivery rate decreased in the stratified resection group (P < 0.05). This study shows that the volume of diseased tissue after stratified resection is significantly less than that of cone tissue, and has less effect on the volume and length of the remaining cervix, and has more advantages in protecting cervical function and reproductive function.